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SCIENCE, SYMPTOMS, AND NARCOLEPSY

  • March 2, 2022
  • thesuperbomb
Narcolepsy
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Introduction

Narcolepsy is a long-term sleep disorder mark by excessive daytime sleepiness and sleep episodes. People with narcolepsy find it difficult to stay awake for long periods of time, regardless of their circumstances. Narcolepsy may cause a lot of problems in your everyday life.

Narcolepsy is often accompany by a lack of muscular tone (cataplexy) cause by powerful emotions. Cataplexy-induced narcolepsy is known as type 1 narcolepsy. Type 2 narcolepsy is that which does not cause cataplexy.

Narcolepsy is divid into two types:

  • The most frequent is Type 1. One of the symptoms is cataplexy, or sudden loss of muscle tone. This kind of drowsiness and cataplexy is cause by low protein levels call hypocretin. (Orexin is another name for hypocretin.)
  • The absence of cataplexy characterizes type 2 narcolepsy. Hypocretin levels in people with type 2 narcolepsy are usually normal.

Symptoms

The signs and symptoms of narcolepsy may worsen in the first few years, but they will last the remainder of your life. They are as follows:

Excessive drowsiness throughout the day. Narcolepsy leads people to fall asleep at inconvenient times and places. You might, for example, be working or speaking with friends when you fall asleep for a few minutes to a half-hour. When you initially wake up, you feel revitalize, but you soon fall asleep again. Modalert and Modvigil tablets can help with this.

Throughout the day, you may notice a decline in attentiveness and attention. Excessive daytime drowsiness is frequently the first symptom and is often the most bothersome, making it difficult to focus and perform normally.

Common Symptoms

  1. Irregular sleep

People with the disease may have difficulty sleeping comfortably at night, only to suffer uncontrollable spells of drowsiness during the day. Narcolepsy patients do not sleep more, but their sleep is fragment and inconsistent throughout the day and night.

  1. Excessive daytime sleepiness

EDS, or Excessive Daytime Sleepiness, is the most frequent symptom of narcolepsy and is closely link to exhaustion. EDS is a feeling of chronic tiredness that causes poor focus and exhaustion. It may be punctuated by moments of “micro sleep,” in which people fall asleep for a little amount of time without realizing it and possibly without interrupting their current work, such as driving or typing.

Muscle tone is suddenly lost.

Cataplexy (KAT-uh-plea-see) is a syndrome that may induce various bodily abnormalities, ranging from slur speech to full muscular weakness, and can persist for a few minutes.

There are several types of cataplexy, including laughter, exhilaration, fear, surprise, and rage. For example, when you laugh, your head may drop uncontrollably, or your knees may collapse unexpectedly.

Some people with narcolepsy may have one or two bouts of cataplexy each year, whereas others have many episodes every day. Cataplexy is not a feature of narcolepsy in everyone.

While Sleeping

Those who suffer from narcolepsy often have trouble moving or talking after falling asleep or waking up. These episodes are generally short (a few seconds or minutes), but they may be terrifying. Even though you did not influence what was occurring, you may be aware of the situation and have no trouble remembering it afterward.

This sort of sleep paralysis is similar to the transient paralysis that happens during rapid eye movement (REM) sleep. REM sleep immobility may hinder your body from acting out dream activities.

Narcolepsy does not always accompany sleep paralysis. Many individuals who do not have narcolepsy have bouts of sleep paralysis.

Rapid eye movement (REM)

In REM sleep, the majority of dreams occur. In people with narcolepsy, REM sleep may happen on any given day. Patients with narcolepsy frequently transition to REM sleep quickly, usually within 15 minutes after falling asleep.

Hallucinations

Because you may not be entirely asleep when you begin dreaming and viewing your dreams as reality, these hallucinations may be very vivid and scary. Hypnagogic hallucinations are hallucinations that are trigger by sleep. Hypnopompic hallucinations are hallucinations that are trigger by waking. You may feel as if someone is in your bedroom when this happens.

Sodium Oxybate

Xyrem is FDA-approve as the sole therapy for cataplexy and excessive daytime drowsiness. There are, however, benefits and drawbacks to discussing it with your doctor. Dehydration, nausea, and sadness are all possible side effects.

The type of pitolisant is the Wakix (pitolisant). Narcolepsy has just been approve for treatment by the FDA. By releasing histamines into the brain, Wakix reduces drowsiness during the day. Aside from headaches and nausea, other possible side effects include anxiety and insomnia. To cure it, take Modalert 200 or Modvigil 200.

Narcolepsy treatment possibilities

Narcolepsy is a long-term sleep disorder. Treatments may help you manage your symptoms even if there is no cure.

This condition may be manage with medications, lifestyle changes, and avoiding dangerous activities.

There are a variety of drugs that can treat narcolepsy, including:

Stimulants

Armodafinil (Nuvigil), modafinil (Provigil), and methylphenidate are among them (Ritalin). This medication has several side effects, including nausea, headaches, and anxiety. All three could help you stay alert.

Inhibitors of serotonin-norepinephrine reuptake

Side effects include digestive problems, sleeplessness, and weight gain. Venlafaxine (Effexor) can treat cataplexy, hallucinations, and sleep paralysis.

In SSRIs, serotonin is block from being reabsorb (SSRIs). You may also sleep better and feel better if you take an SSRI such as fluoxetine (Prozac). You may experience light headedness and a dry mouth, however.

Antidepressants that are tricyclic

Amitriptyline and nortriptyline are two examples. Cataplexy, sleep paralysis, and hallucinations may be reduce. Constipation, dry mouth, and urine retention are possible adverse effects of these older drugs.

Sodium oxybate

The FDA has approve Xyrem as the sole therapy for cataplexy and excessive daytime drowsiness. However, it would help if you discuses the pros and cons of this drug with your doctor. Apart from nausea, sadness, and thirst, there are other possible side effects.

Pitolisant

Wakix releases histamines into the brain, reducing daytime drowsiness. The FDA has just approve it as a treatment for narcolepsy. Various side effects may occur, including headaches, nausea, anxiety, and sleeplessness.

Conclusion

The condition of narcolepsy can be difficult to cope with. Excessive sleepiness is unpleasant, and it’s easy to hurt yourself or others while experiencing it. You can, nevertheless, exert effective control over the circumstance. By getting the appropriate diagnosis, working with your doctor to find the best therapy for you, and following the above instructions, you can keep your health in good shape. Modalert, Modalert 200, Modvigil, Modvigil 200, and Modalert 200 Australia tablets can help with this.

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